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Recommended Assessment Tools Body Composition Analysis (Gold Standard): DEXA (Dual-Energy X-ray Absorptiometry) scanning provides precise body fat percentage, lean mass, and visceral fat measurements

This can be observed in children with SPIGFD, who are deficient in IGF-I as well as IGFBP-3 and ALS, and in whom sc injected rhIGF-I displays a very fast serum clearance rate (118)

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In 13 of 15 patients with baseline B 12 levels, they were 250 pg/mL or below (ranging from 57 pg/ mL to 238 pg/mL)

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